After meeting with Samuel Sterns (Tim Blake Nelson), a scientist who had been researching Bruce’s blood samples, Blonsky persuades Sterns to inject him with his synthesized blood. The injection proves too successful, turning Blonsky into a grotesque, muscle-bound giant aptly referred to as “an abomination.”
Bruce attempts to use the Hulk’s power to stop the Abomination from destroying Harlem. Thankfully, he succeeds, resulting in the Abomination’s arrest.
Source: https://www.distractify.com/p/what-is-the-abomination-she-hulk