In 2021, across the EU NUTS 3 regions, the largest number of residents were in the regions of:
🇪🇸Madrid (6.7 million people)
🇪🇸Barcelona (5.7 million)
🇮🇹Rome (4.2 million)

Smallest in:
🇪🇸El Hierro (11 290)
🇬🇷Evrytania (17 428)
🇦🇹Lungau (20 164)

by @EU_Eurostat