*Dr. Charles is referencing the same study from his TikTok that reported a 54% increased relative risk of dementia. This, again, shows a correlation between the two, but it doesn’t prove anticholinergic drugs (like diphenhydramine) cause dementia. In addition, it was conducted on people over 65, and long-term, regarding this particular study, means over three years of continual use.

Source: https://www.buzzfeed.com/kristatorres/benadryl-dementia-risk-tiktok