In an interview with ComicBook.com, Loki head writer Michael Waldron revealed that Loki would connect to Doctor Strange 2. The question of how, however, might be a bit more nuanced, and the bigger picture might not be available until all episodes of the show and the film are released. “I think everybody will have a better idea of that when on the other end of it,” he said.
“From day one, we were like, ‘Look, this thing should be as vital as a movie.’ There was no cap on our imagination, or on what we could do or what we couldn’t do because it was on Disney Plus.” Michael added, “As far as we were concerned, we were telling the next, most important chapter in the MCU. And so, that meant, ‘Yeah, let’s get Infinity Stones in there.'”
Michael previously revealed that the events of Loki would have “wide-reaching ramifications across the MCU moving forward.” The ominous warnings of Miss Minutes in Episode 1 of Loki about a multiverse “branching off into madness” might not be far off. Even Marvel head Kevin Feige said of Loki, “It perhaps will have more impact on the MCU than any of the shows thus far.”
Source : https://www.distractify.com/p/does-loki-connect-to-doctor-strange-2