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In Spider-Man: Homecoming, Tom Holland’s Spidey discreetly brews his own web fluid in chemistry class to use out in the field. Similarly, Andrew’s Spider-Man repurposes a special substance from Oscorp in The Amazing Spider-Man.
After several failed attempts, he is able to develop his own homemade web fluid, which he puts to immediate use. In a blatant departure, Tobey’s Spider-Man develops his web a little differently in the 2002 Spider-Man film.
Source: https://www.distractify.com/p/why-does-spider-man-need-web-shooters
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