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One Piece Odyssey is not canon to the original manga or anime. Given the game’s current list of playable Straw Hats (i.e, Luffy, Zoro, Nami, Usopp, Sanji, Chopper, Robin, Franky, and Brook), the game is not up to date with the current events of the manga or anime and wouldn’t conceivably fit cleanly at any point in the series’ timeline.
That being said, this hardly comes as a surprise. Many movies and video games of the past take place within the vast open world of One Piece without being canon.
Source: https://www.distractify.com/p/is-one-piece-odyssey-canon
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